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ABCD² Score
The ABCD2 score is a clinical prediction rule used to determine the risk for stroke in the days following a transient ischemic attack (TIA, a condition in which temporary brain dysfunction results from oxygen shortage in the brain). Its usefulness was questioned in a 2015 review as it was not found to separate those who are at low from those who are at high risk of future problems. A high score correctly predicted 87% of the people who did have a stroke in the following 7 days but also many people who did not have problems. The ABCD2 score is based on five parameters (age, blood pressure, clinical features, duration of TIA, and presence of diabetes); scores for each item are added together to produce an overall result ranging between zero and seven. People found to have a high score are often sent to a specialist sooner. Other clinical risk factors, such as atrial fibrillation and anticoagulant, anticoagulation treatment, as well as ongoing or recurrent TIA, are also relevant. The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clinical Prediction Rule
A clinical prediction rule or clinical probability assessment specifies how to use medical signs, symptoms, and other findings to estimate the probability of a specific disease or clinical outcome. Physicians have difficulty in estimated risks of diseases; frequently erring towards overestimation, perhaps due to cognitive biases such as base rate fallacy in which the risk of an adverse outcome is exaggerated. Methods In a prediction rule study, investigators identify a consecutive group of patients who are suspected of having a specific disease or outcome. The investigators then obtain a standard set of clinical observations on each patient and a test or clinical follow-up to define the true state of the patient. They then use statistical methods to identify the best clinical predictors of the patient's true state. The probability of disease will depend on the patient's key clinical predictors. Published methodological standards specify good practices for developing a clinical pred ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |