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4-Bromoaniline
4-Bromoaniline is a compound where an aniline molecule is substituted with a bromine atom on the ''para'' position. Commercially available, this compound may be used as a building block, e.g. in the preparation of p-bromobiphenyl Biphenyl (also known as diphenyl, phenylbenzene, 1,1′-biphenyl, lemonene or BP) is an organic compound that forms colorless crystals. Particularly in older literature, compounds containing the functional group consisting of biphenyl less one ... via the Gomberg-Bachmann reaction. Synthesis 4-bromoaniline can be made by reacting aniline with bromine with a protection with acetyl chloride. References {{DEFAULTSORT:Bromoaniline, 4- Anilines Bromoarenes ...
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Aniline
Aniline is an organic compound with the formula C6 H5 NH2. Consisting of a phenyl group attached to an amino group, aniline is the simplest aromatic amine In organic chemistry, an aromatic amine is an organic compound consisting of an aromatic ring attached to an amine. It is a broad class of compounds that encompasses aniline Aniline is an organic compound with the formula C6 H5 NH2. Consi .... It is an industrially significant Commodity chemicals, commodity chemical, as well as a versatile starting material for fine chemical synthesis. Its main use is in the manufacture of precursors to polyurethane, dyes, and other industrial chemicals. Like most volatile amines, it has the odor of rotten fish. It Combustion, ignites readily, burning with a smoky flame characteristic of aromatic compounds. It is toxic to humans. Relative to benzene, it is electron-rich. It thus participates more rapidly in electrophilic aromatic substitution reactions. Likewise, it is also prone ...
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Bromine
Bromine is a chemical element with the symbol Br and atomic number 35. It is the third-lightest element in group 17 of the periodic table (halogens) and is a volatile red-brown liquid at room temperature that evaporates readily to form a similarly coloured vapour. Its properties are intermediate between those of chlorine and iodine. Isolated independently by two chemists, Carl Jacob Löwig (in 1825) and Antoine Jérôme Balard (in 1826), its name was derived from the Ancient Greek (bromos) meaning "stench", referring to its sharp and pungent smell. Elemental bromine is very reactive and thus does not occur as a native element in nature but it occurs in colourless soluble crystalline mineral halide salts, analogous to table salt. In fact, bromine and all the halogens are so reactive that they form bonds in pairs—never in single atoms. While it is rather rare in the Earth's crust, the high solubility of the bromide ion (Br) has caused its accumulation in the oceans. Commercial ...
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Biphenyl
Biphenyl (also known as diphenyl, phenylbenzene, 1,1′-biphenyl, lemonene or BP) is an organic compound that forms colorless crystals. Particularly in older literature, compounds containing the functional group consisting of biphenyl less one hydrogen (the site at which it is attached) may use the prefixes xenyl or diphenylyl. It has a distinctively pleasant smell. Biphenyl is an aromatic hydrocarbon with a molecular formula (C6H5)2. It is notable as a starting material for the production of polychlorinated biphenyls (PCBs), which were once widely used as dielectric fluids and heat transfer agents. Biphenyl is also an intermediate for the production of a host of other organic compounds such as emulsifiers, optical brighteners, crop protection products, and plastics. Biphenyl is insoluble in water, but soluble in typical organic solvents. The biphenyl molecule consists of two connected phenyl rings. Properties and occurrence Biphenyl occurs naturally in coal tar, crude oil, a ...
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Moses Gomberg
Moses Gomberg (February 8, 1866 – February 12, 1947) was a chemistry professor at the University of Michigan. He was elected to the National Academy of Sciences and served as president of the American Chemical Society. Early life and education He was born in Yelisavetgrad, Russian Empire to a Jewish merchant family. His father was Hershko (Hirsh) Gomberg and his mother was Maryam-Ethel Reznikova. In 1884, the family emigrated to Chicago to escape the pogroms following the assassination of Czar Alexander II. In Chicago he worked at the Stock Yards while attending Lake High School. In 1886, Moses entered the University of Michigan, where he obtained his B.Sc. in 1890 and his doctorate in 1894 under the supervision of A. B. Prescott. His thesis, titled "''Trimethylxanthine and Some of its Derivatives''", dealt with the derivatization of caffeine. Career Appointed an instructor in 1893, Gomberg worked at the University of Michigan for the duration of his professional academic ...
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Werner Emmanuel Bachmann
Werner Emmanuel Bachmann (November 13, 1901 – March 22, 1951) was an American chemist. Bachmann was born in Detroit, Michigan where he studied chemistry and chemical engineering at Wayne State University and later at the University of Michigan in Ann Arbor nearby. He completed his doctorate under Moses Gomberg and spent the rest of his academic career at the University of Michigan. Bachmann studied physical organic chemistry (rearrangements, free radicals) and organic synthesis. He is considered a pioneer in steroid synthesis, and carried out the first total synthesis of a steroidal hormone, equilenin with Alfred L. Wilds. His name is associated with the Gomberg-Bachmann reaction for the synthesis of diaryl compounds from aryl diazonium chlorides. Bachmann developed a new method for the production of the explosive RDX, which was used by the United States during World War II World War II or the Second World War, often abbreviated as WWII or WW2, was a world ...
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