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3,4-dihydroxybenzoate
Protocatechuic acid (PCA) is a dihydroxybenzoic acid, a type of phenolic acid. It is a major metabolite of antioxidant polyphenols found in green tea. It has mixed effects on normal and cancer cells in ''in vitro'' and ''in vivo'' studies. Biological effects Protocatechuic acid (PCA) is antioxidant and anti-inflammatory. PCA extracted from ''Hibiscus sabdariffa'' protected against chemically induced liver toxicity ''in vivo''. ''In vitro'' testing documented antioxidant and anti-inflammatory activity of PCA, while liver protection ''in vivo'' was measured by chemical markers and histological assessment. PCA has been reported to induce apoptosis of human leukemia cells, as well as malignant HSG1 cells taken from human oral cavities, but PCA was found to have mixed effects on TPA-induced mouse skin tumours. Depending on the amount of PCA and the time before application, PCA could reduce or enhance tumour growth. Similarly, PCA was reported to increase proliferation and inhibit ap ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
4-hydroxybenzoate 3-monooxygenase (NAD(P)H)
In enzymology, a 4-hydroxybenzoate 3-monooxygenase AD(P)H'' () is an enzyme that catalyzes the chemical reaction :4-hydroxybenzoate + NAD(P)H + H+ + O2 \rightleftharpoons 3,4-dihydroxybenzoate + NAD(P)+ + H2O The 5 substrates of this enzyme are 4-hydroxybenzoate, NADH, NADPH, H+, and O2, whereas its 4 products are 3,4-dihydroxybenzoate, NAD+, NADP+, and H2O. This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of one atom o oxygen into the other donor. The systematic name of this enzyme class is 4-hydroxybenzoate,NAD(P)H:oxygen oxidoreductase (3-hydroxylating). Other names in common use include 4-hydroxybenzoate 3-monooxygenase (reduced nicotinamide adenine, dinucleotide (phosphate)), 4-hydroxybenzoate-3-hydroxylase, and 4-hydroxybenzoate 3-hydroxylase. This enzyme p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
3-hydroxybenzoate 4-monooxygenase
In enzymology, a 3-hydroxybenzoate 4-monooxygenase () is an enzyme that catalyzes the chemical reaction :3-hydroxybenzoate + NADPH + H+ + O2 \rightleftharpoons 3,4-dihydroxybenzoate + NADP+ + H2O The 4 substrates of this enzyme are 3-hydroxybenzoate, NADPH, H+, and O2, whereas its 3 products are 3,4-dihydroxybenzoate, NADP+, and H2O. This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of one atom o oxygen into the other donor. The systematic name of this enzyme class is 3-hydroxybenzoate,NADPH:oxygen oxidoreductase (4-hydroxylating). This enzyme is also called 3-hydroxybenzoate 4-hydroxylase. This enzyme participates in benzoate degradation via hydroxylation and 2,4-dichlorobenzoate degradation. It employs one cofactor, FAD. Structural studies As of late 2007 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Terephthalate 1,2-cis-dihydrodiol Dehydrogenase
In enzymology, a terephthalate 1,2-cis-dihydrodiol dehydrogenase () is an enzyme that catalyzes the chemical reaction: :cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,4-dicarboxylate + NAD+ \rightleftharpoons 3,4-dihydroxybenzoate + CO2 + NADH Thus, the two substrates of this enzyme are cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,4-dicarboxylate and NAD+, whereas its 3 products are 3,4-dihydroxybenzoate, CO2, and NADH. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivial ... of this enzyme class is cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,4-dicarboxylate:NAD+ oxidoreductase (decarboxylating). This enzyme participates in 2,4-dich ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
(3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate Dehydrogenase
In enzymology, a (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase () is an enzyme that catalyzes the chemical reaction :(3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD \rightleftharpoons 3,4-dihydroxybenzoate + CO + NADH Thus, the two substrates of this enzyme are (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate and NAD, whereas its 3 products are 3,4-dihydroxybenzoate, CO, and NADH. This enzyme is a part of the terephthalate degradation pathway in bacteria. Family This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate:NAD+ oxidoreductase. Another name in common use is (1R,2S)-dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase. This enzyme employs one cofactor, iron Iron () is a chemical element with symbol Fe (from ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
3-dehydroshikimate Dehydratase
3-dehydroshikimate dehydratase () is an enzyme with systematic name ''3-dehydroshikimate hydro-lyase''. This enzyme catalyses the following chemical reaction A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the pos ... : 3-dehydro-shikimate \rightleftharpoons 3,4-dihydroxybenzoate + H2O This enzyme catalyses an early step in the biosynthesis of petrobactin. References External links * {{Portal bar, Biology, border=no EC 4.2.1 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Insect Cuticle
The cuticle forms the major part of the integument of the Arthropoda. It includes most of the material of the exoskeleton of the insects, Crustacea, Arachnida, and Myriapoda. Morphology In arthropods, the integument, the external "skin", or "shell", is the product of a single layer of ectodermal epithelium. That layer is attached to the external or distal surface of the deepest layer, the non-cellular internal membrane of the integument. That non-cellular membrane is called the basement membrane. The layer of epithelium on the basement membrane produces the cuticle, which begins as a tough, flexible layer of chitin. Such thin, flexible chitin is the major structural part of the integument where flexibility is necessary, such as in bodily parts that must stretch to contain accumulated liquids, or that form joints between rigid parts of the exoskeleton. In other parts of the cuticle the function of the integument demands more rigid materials, such as armoured regions or the biting ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Green Tea
Green tea is a type of tea that is made from '' Camellia sinensis'' leaves and buds that have not undergone the same withering and oxidation process which is used to make oolong teas and black teas. Green tea originated in China, and since then its production and manufacture has spread to other countries in East Asia. Several varieties of green tea exist, which differ substantially based on the variety of ''C. sinensis'' used, growing conditions, horticultural methods, production processing, and time of harvest. The two main components unique to green tea are "catechins" and "theanine," and the health effects of these components are attracting a great deal of attention in Japan and abroad. History Tea consumption has its legendary origins in China during the reign of mythological Emperor Shennong. A book written by Lu Yu in 618–907 AD (Tang dynasty), ''The Classic of Tea'' (), is considered important in green tea history. The ''Kissa Yōjōki'' (喫茶養生記 ''Book ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Metabolite
In biochemistry, a metabolite is an intermediate or end product of metabolism. The term is usually used for small molecules. Metabolites have various functions, including fuel, structure, signaling, stimulatory and inhibitory effects on enzymes, catalytic activity of their own (usually as a cofactor to an enzyme), defense, and interactions with other organisms (e.g. pigments, odorants, and pheromones). A primary metabolite is directly involved in normal "growth", development, and reproduction. Ethylene exemplifies a primary metabolite produced large-scale by industrial microbiology. A secondary metabolite is not directly involved in those processes, but usually has an important ecological function. Examples include antibiotics and pigments such as resins and terpenes etc. Some antibiotics use primary metabolites as precursors, such as actinomycin, which is created from the primary metabolite tryptophan. Some sugars are metabolites, such as fructose or glucose, which are both p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phellinus Linteus
''Phellinus linteus'' (Japanese "meshimakobu", Chinese "song gen", Korean "sanghwang", English "mesima", American English "black hoof mushroom") is a mushroom. It is shaped like a hoof, has a bitter taste, and in the wild grows on mulberry trees. The stem color is dark brown to black. Uses In Asian traditional medicine, the mushroom is prepared as a tea. Extracts containing polysaccharide-protein complexes from ''P. linteus'' are promoted in Asia for potential anti-cancer activities, but there is insufficient evidence from clinical studies to indicate its use as a prescription drug to treat cancer or any disease. Its processed mycelium may be sold as a dietary supplement in the form of capsules, pills or powder. See also *Medicinal fungi Medicinal fungi are fungi that contain metabolites or can be induced to produce metabolites through biotechnology to develop prescription drugs. Compounds successfully developed into drugs or under research include antibiotics, an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Agaricus Bisporus
''Agaricus bisporus'' is an edible basidiomycete mushroom native to grasslands in Eurasia and North America. It has two color states while immature – white and brown – both of which have various names, with additional names for the mature state. ''A. bisporus'' is cultivated in more than seventy countries and is one of the most commonly and widely consumed mushrooms in the world. Names When immature and , this mushroom may be known as: * common mushroom * white mushroom * button mushroom * cultivated mushroom * table mushroom * champignon ( French for mushroom) When immature and , it may be known variously as: * Swiss brown mushroom * Roman brown mushroom * Italian brown mushroom * cremini/crimini mushroom * chestnut mushroom (not to be confused with '' Pholiota adiposa'') * baby bella When marketed in its mature state, the mushroom is brown with a cap measuring . This form is commonly sold under the names portobello, portabella, or portobella; the etymology is dispute ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Roselle (plant)
Roselle (''Hibiscus sabdariffa'') is a species of flowering plant in the genus ''Hibiscus'' that is native to Africa, most likely West Africa and also found in India especially Maharashtra with local name ambali. In the 16th and early 17th centuries it was spread to the West Indies and Asia, respectively, where it has since become naturalized in many places. The stems are used for the production of bast fibre and the dried cranberry-tasting calyces are commonly steeped to make a popular infusion known as carcade. Description Roselle is an annual or perennial herb or woody-based subshrub, growing to tall. The leaves are deeply three- to five-lobed, long, arranged alternately on the stems. The flowers are in diameter, white to pale yellow with a dark red spot at the base of each petal, and have a stout, conspicuous calyx at the base, wide, enlarging to and becoming fleshy and a deep crimson red as the fruit matures, which takes about six months. Names Asia Roselle is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Allium Cepa
An onion (''Allium cepa'' L., from Latin ''cepa'' meaning "onion"), also known as the bulb onion or common onion, is a vegetable that is the most widely cultivated species of the genus ''Allium''. The shallot is a botanical variety of the onion which was classified as a separate species until 2010. Its close relatives include garlic, scallion, leek, and chive. This genus also contains several other species variously referred to as onions and cultivated for food, such as the Japanese bunching onion (''Allium fistulosum''), the tree onion (''A.'' × ''proliferum''), and the Canada onion (''Allium canadense''). The name ''wild onion'' is applied to a number of ''Allium'' species, but ''A. cepa'' is exclusively known from cultivation. Its ancestral wild original form is not known, although escapes from cultivation have become established in some regions. The onion is most frequently a biennial or a perennial plant, but is usually treated as an annual and harvested in its fi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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