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25C-NBOH
25-C-NBOH (2C-C-NBOH, NBOH-2CC) is a derivative of the phenethylamine derived hallucinogen 2C-C which has been sold as a designer drug. It has similar serotonin receptor affinity to the better-known compound 25C-NBOMe. Analogues and derivatives * 25C-NBF * 25C-NBMD * 25C-NBOH * 25C-NBOMe (NBOMe-2CC) * 25C-NB3OMe 25C-NB3OMe (2C-C-NB3OMe, NB3OMe-2C-C) is a derivative of the phenethylamine hallucinogen 2C-C, which acts as a highly potent partial agonist for the human Humans (''Homo sapiens'') are the most abundant and widespread species of prima ... * 25C-NB4OMe * 25I-NBOH * 25B-NBOH * 25E-NBOH * 25H-NBOH Analytical chemistry 25C-NBOH undergoes degradation under routine Gas Chromatography (GC) conditions, as well as other NBOH's substances, into 2C-C. An alternative method proposed for reliable identification of 25I-NBOH using GC/MS may be used for 25C-NBOH analysis. Legality United Kingdom References 25-NB (psychedelics) Chlorobenzenes D ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
25-NB (psychedelics)
The 25-NB (25''x''-NB''x'') series, sometimes alternatively referred to as the NBOMe compounds, is a family of serotonergic psychedelics. They are substituted phenethylamines and were derived from the 2C family. They act as selective agonists of the serotonin 5-HT2A receptor. The 25-NB family is unique relative to other classes of psychedelics in that they are, generally speaking, extremely potent and relatively selective for the 5-HT2A receptor. Use of NBOMe series drugs has caused many deaths and hospitalisations since the drugs popularisation in the 2010s. This is primarily due to their high overdose potential and sellers passing off the compounds in the series as LSD. Chemical structure The 25-NB compounds are mostly ''N''-benzylphenethylamines, though in some cases the phenyl ring of the N-benzyl group is replaced by other heterocycles such as thiophene, pyridine, furan, tetrahydrofuran, benzodioxole or naphthalene, among others. Generally speaking, they have methox ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
25E-NBOH
25E-NBOH (2C-E-NBOH, NBOH-2C-E) is a derivative of the phenethylamine derived hallucinogen 2C-E. It was first developed by Martin Hansen at the University of Copenhagen in 2010 as a brain imaging agent, but has subsequently been sold as a designer drug, first being identified in Brazil in 2018 on seized blotter paper, as well as in Slovenia. It acts as a potent serotonin receptor agonist with similar affinity to better-known compounds such as 25I-NBOMe at 5-HT2A and 5-HT2C receptors. Legal status United Kingdom See also * 4-EA-NBOMe * DOET * 2C-TFE * 2C-E-FLY 2C-E-FLY is a recreational designer drug A designer drug is a structural or functional analog of a controlled substance that has been designed to mimic the pharmacological effects of the original drug, while avoiding classification as illega ... References 25-NB (psychedelics) Designer drugs Phenols Phenethylamines {{hallucinogen-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2C-C
2C-C is a Psychedelics, dissociatives and deliriants, psychedelic drug of the 2C (psychedelics), 2C family. It was first synthesized by Alexander Shulgin, sometimes used as an entheogen. In his book ''PiHKAL, PiHKAL (Phenethylamines i Have Known And Loved)'', Shulgin lists the dosage range as 20–40 mg. 2C-C is usually taken orally, but may also be insufflated. 2C-C is Controlled Substances Act#Schedule I controlled substances, schedule I of section 202(c) of the Controlled Substances Act in the United States, signed into law as of July, 2012 under the Food and Drug Administration Safety and Innovation Act. Not much information is known about the toxicity of 2C-C. Effects Over the approximate dose range 20–40 mg, visual effects last approximately 4 to 8 hours. Drug prohibition laws China As of October 2015 2C-C is a controlled substance in China. Canada As of October 31, 2016; 2C-C is a controlled substance (Schedule III) in Canada. Germany 2C-C is an Drugs contro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
25B-NBOH
25B-NBOH (2C-B-NBOH, NBOH-2C-B) is a derivative of the phenethylamine derived hallucinogen 2C-B which has been sold as a designer drug A designer drug is a structural or functional analog of a controlled substance that has been designed to mimic the pharmacological effects of the original drug, while avoiding classification as illegal and/or detection in standard drug tests. D .... It acts as a potent serotonin receptor agonist with similar affinity to the better-known compound 25B-NBOMe at 5-HT2A and 5-HT2C receptors with values of 8.3 and 9.4, respectively. Legal status Sweden The Riksdag added 25B-NBOH to Narcotic Drugs Punishments Act under Swedish Schedule I (''"substances, plant materials and fungi which normally do not have medical use"'') as of January 26, 2016, published by Medical Products Agency (MPA) in regulation ''HSLF-FS 2015:35'' listed as 25B-NBOH, and 2-( -(4-bromo-2,5-dimetoxifenyl)etylaminoetyl)fenol. United Kingdom Analogues and derivatives ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chlorobenzenes
Chlorobenzene is an aromatic organic compound with the chemical formula C6H5Cl. This colorless, flammable liquid is a common solvent and a widely used intermediate in the manufacture of other chemicals. Uses Historical The major use of chlorobenzene is as an intermediate in the production of herbicides, dyestuffs, and rubber. Chlorobenzene is also used as a high-boiling solvent in industrial applications as well as in the laboratory. Chlorobenzene is nitrated on a large scale to give a mixture of 2-nitrochlorobenzene and 4-nitrochlorobenzene, which are separated. These mononitrochlorobenzenes are converted to related 2-nitrophenol, 2-nitroanisole, bis(2-nitrophenyl)disulfide, and 2-nitroaniline by nucleophilic displacement of the chloride, with respectively sodium hydroxide, sodium methoxide, sodium disulfide, and ammonia. The conversions of the 4-nitro derivative are similar. Chlorobenzene once was used in the manufacture of pesticides, most notably DDT, by reaction with ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gas Chromatography
Gas chromatography (GC) is a common type of chromatography used in analytical chemistry for separating and analyzing compounds that can be vaporized without decomposition. Typical uses of GC include testing the purity of a particular substance, or separating the different components of a mixture. In preparative chromatography, GC can be used to prepare pure compounds from a mixture. Gas chromatography is also sometimes known as vapor-phase chromatography (VPC), or gas–liquid partition chromatography (GLPC). These alternative names, as well as their respective abbreviations, are frequently used in scientific literature. Gas chromatography is the process of separating compounds in a mixture by injecting a gaseous or liquid sample into a mobile phase, typically called the carrier gas, and passing the gas through a stationary phase. The mobile phase is usually an inert gas or an unreactive gas such as helium, argon, nitrogen or hydrogen. The stationary phase is a microscopic la ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
25I-NBOH
25I-NBOH (NBOH-2CI, Cimbi-27, 2-C-I-NBOH) is a derivative of the phenethylamine-derived hallucinogen 2C-I that was discovered in 2006 by a team at Purdue University. Pharmacology 25I-NBOH acts as a potent agonist of the 5HT2A receptor, with a Ki of 0.061 nM at the human 5HT2A receptor, similar to the better-known compound 25I-NBOMe, making it some twelve times the potency of 2C-I itself. Although ''in vitro'' tests show this compound acts as an agonist, animal studies to confirm these findings have not been reported. While the ''N''-benzyl derivatives of 2C-I had significantly increased binding to 5HT2A receptor fragments, compared to 2C-I, the ''N''-benzyl derivatives of DOI were less active compared to DOI. 25I-NBOH is notable as one of the most selective agonist ligands for the 5-HT2A receptor with an EC50 value of 0.074 nM with more than 400 times selectivity over the 5-HT2C receptor. Analytical chemistry 25I-NBOH is a labile molecule which fragments into ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Designer Drug
A designer drug is a structural or functional analog of a controlled substance that has been designed to mimic the pharmacological effects of the original drug, while avoiding classification as illegal and/or detection in standard drug tests. Designer drugs include psychoactive substances that have been designated by the European Union as new psychoactive substances (NPS) as well as analogs of performance-enhancing drugs such as designer steroids. Some of these were originally synthesized by academic or industrial researchers in an effort to discover more potent derivatives with fewer side effects, and shorter duration (and possibly also because it is easier to apply for patents for new molecules) and were later co-opted for recreational use. Other designer drugs were prepared for the first time in clandestine laboratories. Because the efficacy and safety of these substances have not been thoroughly evaluated in animal and human trials, the use of some of these drugs may result i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
25C-NB4OMe
25C-NB4OMe (2C-C-NB4OMe, NB4OMe-2C-C) is a derivative of the phenethylamine hallucinogen 2C-C, which acts as a highly potent partial agonist for the human 5-HT2A receptor Receptor may refer to: * Sensory receptor, in physiology, any structure which, on receiving environmental stimuli, produces an informative nerve impulse *Receptor (biochemistry), in biochemistry, a protein molecule that receives and responds to a ....https://bitnest.netfirms.com/external.php?id=%2501%253B5%25168%250F%2518%250DG%257F%255B18%2521UYHZP%251CUTscc%250BWk Legality United Kingdom References {{Phenethylamines 25-NB (psychedelics) Designer drugs ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
25C-NB3OMe
25C-NB3OMe (2C-C-NB3OMe, NB3OMe-2C-C) is a derivative of the phenethylamine hallucinogen 2C-C, which acts as a highly potent partial agonist for the human Humans (''Homo sapiens'') are the most abundant and widespread species of primate, characterized by bipedalism and exceptional cognitive skills due to a large and complex brain. This has enabled the development of advanced tools, cultu ... 5-HT2A receptor.https://bitnest.netfirms.com/external.php?id=%2501%253B5%25168%250F%2518%250DG%257F%255B18%2521UYHZP%251CUTscc%250BWk Legality United Kingdom References {{Phenethylamines 25-NB (psychedelics) Designer drugs ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
