Pyloric Glands
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Pyloric Glands
The gastric glands are glands in the lining of the stomach that play an essential role in the process of digestion. All of the glands have mucus-secreting foveolar cells. Mucus lines the entire stomach, and protects the stomach lining from the effects of hydrochloric acid released from other cells in the glands. There are two types of gland in the stomach, the oxyntic gland, and the pyloric gland. The major type of gastric gland is the oxyntic gland that is present in 80 per cent of the stomach, and is often referred to simply as the ''gastric gland''. The oxyntic gland is an exocrine gland and contains the parietal cells that produce hydrochloric acid, and intrinsic factor. Intrinsic factor is necessary for the absorption of vitamin B12. The other type of gland in the stomach is the pyloric gland found in the pyloric region taking up the remaining 20 per cent of the stomach area. The pyloric gland secretes gastrin from its G cells. Pyloric glands are similar in structure t ...
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Gland
In animals, a gland is a group of cells in an animal's body that synthesizes substances (such as hormones) for release into the bloodstream (endocrine gland) or into cavities inside the body or its outer surface (exocrine gland). Structure Development Every gland is formed by an ingrowth from an epithelial surface. This ingrowth may in the beginning possess a tubular structure, but in other instances glands may start as a solid column of cells which subsequently becomes tubulated. As growth proceeds, the column of cells may split or give off offshoots, in which case a compound gland is formed. In many glands, the number of branches is limited, in others (salivary, pancreas) a very large structure is finally formed by repeated growth and sub-division. As a rule, the branches do not unite with one another, but in one instance, the liver, this does occur when a reticulated compound gland is produced. In compound glands the more typical or secretory epithelium is found forming t ...
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Gastric Pit
Gastric pits are indentations in the stomach which denote entrances to 3-5"Secretions from several gastric glands flow into each gastric pit" Principals of Anatomy & Physiology 15th Ed 2017, Gerard Tortora & Bryan Derrickson tubular shaped gastric glands. They are deeper in the pylorus than they are in the other parts of the stomach. The human stomach has several million of these pits which dot the surface of the lining epithelium. Surface mucous cells line the pits themselves but give way to a series of other types of cells which then line the glands themselves. Gastric acid Gastric acid also known as ''gastric juice'' is secreted from gastric glands, which are located in narrow tube like structures called gastric pits. Gastric juice contains hydrochloric acid, pepsinogen and mucus Mucus ( ) is a slippery aqueous secretion produced by, and covering, mucous membranes. It is typically produced from cells found in mucous glands, although it may also originate from mixed glan ...
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Foveolar Cell
Foveolar cells or surface mucous cells are mucus-producing cells which cover the inside of the stomach, protecting it from the corrosive nature of gastric acid. These cells line the gastric mucosa (mucous neck cells are found in the necks of the gastric pits). The mucus-secreting cells of the stomach can be distinguished histologically from the intestinal goblet cells, another type of mucus-secreting cell. Structure The gastric mucosa that lines the inner wall of the stomach has a set of microscopic features called gastric glands which, depending on the location within the stomach, secrete different substances into the lumen of the organ. The openings of these glands into the stomach are called gastric pits which foveolar cells line in order to provide a protective alkaline secretion against the corrosive gastric acid. Microanatomy Foveolar cells line the surface of the stomach, the gastric pits, and the top part of gastric glands: the neck. They constitute a simple columnar e ...
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G Cells
In anatomy, the G cell or gastrin cell, is a type of cell in the stomach and duodenum that secretes gastrin. It works in conjunction with gastric chief cells and parietal cells. G cells are found deep within the pyloric glands of the stomach antrum, and occasionally in the pancreas and duodenum. The vagus nerve innervates the G cells. Gastrin-releasing peptide is released by the post-ganglionic fibers of the vagus nerve onto G cells during parasympathetic stimulation. The peptide hormone bombesin also stimulates gastrin from G cells. Gastrin-releasing peptide, as well as the presence of amino acids in the stomach, stimulates the release of gastrin from the G cells. Gastrin stimulates enterochromaffin-like cells to secrete histamine. Gastrin also targets parietal cells by increasing the amount of histamine and the direct stimulation by gastrin, causing the parietal cells to increase HCl secretion in the stomach. G-cells frequently express PD-L1 during homeostasis which protects t ...
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Pylorus
The pylorus ( or ), or pyloric part, connects the stomach to the duodenum. The pylorus is considered as having two parts, the ''pyloric antrum'' (opening to the body of the stomach) and the ''pyloric canal'' (opening to the duodenum). The ''pyloric canal'' ends as the ''pyloric orifice'', which marks the junction between the stomach and the duodenum. The orifice is surrounded by a sphincter, a band of muscle, called the ''pyloric sphincter''. The word ''pylorus'' comes from Greek πυλωρός, via Latin. The word ''pylorus'' in Greek means "gatekeeper", related to "gate" ( el, pyle) and is thus linguistically related to the word " pylon". Structure The pylorus is the furthest part of the stomach that connects to the duodenum. It is divided into two parts, the ''antrum'', which connects to the body of the stomach, and the ''pyloric canal'', which connects to the duodenum. Antrum The ''pyloric antrum'' is the initial portion of the pylorus. It is near the bottom of the stomach, ...
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Antrum
''This is a disambiguation page for the biological term. For the 2018 horror movie, see Antrum (film)'' In biology, antrum is a general term for a cavity or chamber, which may have specific meaning in reference to certain organs or sites in the body. In vertebrates, it may refer specifically to: * Antrum follicularum, the cavity in the epithelium that envelops the oocyte * Mastoid antrum, a cavity between the middle ear and temporal bone in the skull * Stomach antrum, either ** Pyloric antrum, the lower portion of the stomach. This is what is usually referred to as "antrum" in stomach-related topics{{citation needed, date=November 2019 ** or Antrum cardiacum, a dilation that occurs in the esophagus near the stomach (forestomach) * Maxillary antrum or antrum of Highmore, the maxillary sinus, a cavity in the maxilla and the largest of the paranasal sinuses In invertebrates, it may refer specifically to: * Antrum of female lepidoptera genitalia The study of the genitalia of Lepid ...
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Fundus (stomach)
The stomach is a muscular, hollow organ in the gastrointestinal tract of humans and many other animals, including several invertebrates. The stomach has a dilated structure and functions as a vital organ in the digestive system. The stomach is involved in the gastric phase of digestion, following chewing. It performs a chemical breakdown by means of enzymes and hydrochloric acid. In humans and many other animals, the stomach is located between the oesophagus and the small intestine. The stomach secretes digestive enzymes and gastric acid to aid in food digestion. The pyloric sphincter controls the passage of partially digested food (chyme) from the stomach into the duodenum, where peristalsis takes over to move this through the rest of intestines. Structure In the human digestive system, the stomach lies between the oesophagus and the duodenum (the first part of the small intestine). It is in the left upper quadrant of the abdominal cavity. The top of the stomach lies agains ...
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Brunner's Glands
Brunner's glands (or duodenal glands) are compound tubular submucosal glands found in that portion of the duodenum which is above the hepatopancreatic sphincter (i.e sphincter of Oddi). It also contains submucosa which creates special glands. The main function of these glands is to produce a mucus-rich alkaline secretion i.e. mucous (containing bicarbonate) in order to: * protect the duodenum from the acidic content of chyme (which is introduced into the duodenum from the stomach); * provide an alkaline condition for the intestinal enzymes to be active, thus enabling absorption to take place; * lubricate the intestinal walls. * They also secrete epidermal growth factor, which inhibits parietal and chief cells of the stomach from secreting acid and their digestive enzymes. This is another form of protection for the duodenum. They are the distinguishing feature of the duodenum, and are named for the Swiss physician who first described them, Johann Conrad Brunner. Structure H ...
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Duodenal
The duodenum is the first section of the small intestine in most higher vertebrates, including mammals, reptiles, and birds. In fish, the divisions of the small intestine are not as clear, and the terms anterior intestine or proximal intestine may be used instead of duodenum. In mammals the duodenum may be the principal site for iron absorption. The duodenum precedes the jejunum and ileum and is the shortest part of the small intestine. In humans, the duodenum is a hollow jointed tube about 25–38 cm (10–15 inches) long connecting the stomach to the middle part of the small intestine. It begins with the duodenal bulb and ends at the suspensory muscle of duodenum. Duodenum can be divided into four parts: the first (superior), the second (descending), the third (horizontal) and the fourth (ascending) parts. Structure The duodenum is a C-shaped structure lying adjacent to the stomach. It is divided anatomically into four sections. The first part of the duodenum lie ...
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Compound Racemose Glands
Alveolar glands, also called saccular glands are glands with a saclike secretory portion, in conrast with tubular glands. They typically have an enlarged lumen (cavity), hence the name: they have a shape similar to alveoli, the very small air sacs in the lungs. Some sources draw a clear distinction between acinar and alveolar glands, based upon the size of the lumen. A further complication in the case of the alveolar glands may occur in the form of still smaller saccular diverticuli growing out from the main sacculi. The term "racemose gland" is used to describe a "compound alveolar gland" or "compound acinar gland." Branched alveolar glands are classified as follows: Additional images File:Gray897.png, Alveoli of lacrimal gland. File:Gray1026.png, Human submaxillary gland. At the right is a group of mucous alveoli, at the left a group of serous alveoli. File:Gray1173.png, Section of portion of mamma. See also * Acinus An acinus (; plural, acini; adjective, aci ...
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Simple Tubular Glands
Tubular glands are glands with a tube-like shape throughout their length, in contrast with alveolar glands, which have a saclike secretory portion. Tubular glands are further classified as one of the following types: Additional images See also * skin - glands in skin structure * hair follicles - for hair growth References Additional images File:Gray940.png, A diagrammatic sectional view of the skin (magnified). File:Gray1169.png, Vertical section of mucous membrane of human uterus The uterus (from Latin ''uterus'', plural ''uteri'') or womb () is the organ in the reproductive system of most female mammals, including humans that accommodates the embryonic and fetal development of one or more embryos until birth. The .... File:Skin.png, Skin Glands {{anatomy-stub ...
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Cardia
The stomach is a muscular, hollow organ in the gastrointestinal tract of humans and many other animals, including several invertebrates. The stomach has a dilated structure and functions as a vital organ in the digestive system. The stomach is involved in the gastric phase of digestion, following chewing. It performs a chemical breakdown by means of enzymes and hydrochloric acid. In humans and many other animals, the stomach is located between the oesophagus and the small intestine. The stomach secretes digestive enzymes and gastric acid to aid in food digestion. The pyloric sphincter controls the passage of partially digested food (chyme) from the stomach into the duodenum, where peristalsis takes over to move this through the rest of intestines. Structure In the human digestive system, the stomach lies between the oesophagus and the duodenum (the first part of the small intestine). It is in the left upper quadrant of the abdominal cavity. The top of the stomach lies agains ...
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